I think there's a difference depending on whether you're looking from a local or a macro perspective. Some scenarios / engines mean more local pollution but less global impact. The idea of causing more pollution but keeping it away from populations (for example, going a longer way around a city rather than through it) is attractive when it comes to the former but at cost to the latter
What I'm trying to say is, it's not black and white as just looking at the numbers, but where they're applied
In the past that was the thinking, my pollution* is not a problem because the atmosphere is so vast, the wind will just carry my pollution away from me but the atmosphere is a finite size, and some pollutants have a very long life, we now find we can, and are, polluting the Earth.
CFC's were a good example, in their heyday they were freely discharged into the atmosphere, until we discovered they did not decompose but had a very long life and interacted with the Ozone layer, allowing more Ultraviolet light through.
Once this was recognised, most countries started to use other gases in place of CFC's, and now the Ozone layer is reforming.
*Including Carbon Dioxide.