I have had to deal with the aftermath of this liquid tyre repair stuff on a number of occasions, and when I have attended forensic tyre courses with the likes of Dunlop and Michelin, you can see their eyes roll as soon as liquid tyre repair products are mentioned.
The first issue I came across (mainly on motorcycles but on cars as well from time to time) is how the goo can cause the wheels to become imbalanced creating wheel wobble as it counteracts the balance weights that were fitted when the tyres were balanced previously.
In some cases the imbalance can be quite severe (dramatic on the front wheel of a bike) and I have had a couple a fatalities where the cause of the crash (and subsequently cause of death) was attributed to the out of balance wheels caused by the liquid tyre repair stuff.
The other issue is the damage it can do to the inside of the rims. I have my own commercial tyre changing and wheel balancing equipment, so friends often get a set of tyres and ask if I can do the change for them.
The mess this tyre repair stuff makes is horrendous, and even though you can spend hours trying to clean it all off, even the slightest residue can prevent the tyre beading properly and you end up with a very slow air lea from the beading.
If the tyre id punctured within 50% of the centre of the tyre and the sidewall is not compromised, then it can be plugged and repaired using a vulcanised mushroom.
But..... Here again the goo stops the mushroom vulcanising properly, and so you run the risk of the original puncture hole continuing to leak as the mushroom starts to lift.
I could go on, but I am sure you get the drift, and as you might have gathered I am not a fan of liquid repair stuff, nor am I fan of the external repair kits where you push a plug in from the outside which runs the high risk of delaminating the tyre, especially on bike tyres, but I have seen car tyres blow from this as well which is worrying as by and large you do not get instant deflation as a rule as the air can only escape from where the hole is, but delamination puts paid to that theory and when they go, boy do they go as some of you more senior drivers might well have experienced during your driving career